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Dinesh P de Alwis Selected Research

LY 293111 (LY293111)

6/2007A phase I study of oral LY293111 given daily in combination with irinotecan in patients with solid tumours.
8/2005Phase I and pharmacokinetic study of LY293111, an orally bioavailable LTB4 receptor antagonist, in patients with advanced solid tumors.

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Dinesh P de Alwis Research Topics

Disease

17Neoplasms (Cancer)
02/2021 - 12/2002
4Melanoma (Melanoma, Malignant)
12/2018 - 10/2011
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2018 - 01/2008
3Neutropenia
02/2013 - 01/2007
2Body Weight (Weight, Body)
02/2013 - 10/2011
2Thrombocytopenia (Thrombopenia)
02/2013 - 01/2013
1Cachexia
12/2018
1Anorexia
12/2018
1Neoplasm Metastasis (Metastasis)
10/2018
1Sarcoma (Soft Tissue Sarcoma)
02/2013
1Breast Neoplasms (Breast Cancer)
01/2008
1Abdominal Pain (Pain, Abdominal)
06/2007
1Diarrhea
06/2007
1Febrile Neutropenia
08/2005

Drug/Important Bio-Agent (IBA)

5pembrolizumabIBA
02/2021 - 10/2018
5SodiumIBA
02/2013 - 10/2011
5N- ((5- bromo- 2- thienyl)sulfonyl)- 2,4- dichlorobenzamideIBA
02/2013 - 10/2011
3Pharmaceutical PreparationsIBA
01/2020 - 01/2013
2Docetaxel (Taxotere)FDA Link
12/2018 - 11/2004
2Antineoplastic Agents (Antineoplastics)IBA
01/2016 - 02/2013
2LY 293111 (LY293111)IBA
06/2007 - 08/2005
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
11/2004 - 12/2002
1Biological ProductsIBA
01/2021
1Monoclonal AntibodiesIBA
01/2021
1B7-H1 AntigenIBA
10/2018
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2018
1LY-2157299IBA
01/2008
1Phosphotransferases (Kinase)IBA
01/2008
1Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
01/2008
1LipoxygenasesIBA
06/2007
1Arachidonic Acid (Vitamin F)IBA
06/2007
1Irinotecan (Camptosar)FDA LinkGeneric
06/2007
1Methotrexate (Mexate)FDA LinkGeneric
01/2007
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2007
1Biomarkers (Surrogate Marker)IBA
01/2007
1Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA
08/2005
1Vinorelbine (Navelbine)FDA LinkGeneric
08/2005
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2002
1zosuquidar trihydrochloride (LY335979)IBA
12/2002

Therapy/Procedure

3Drug Therapy (Chemotherapy)
02/2013 - 01/2007
1Therapeutics
01/2020
1Intravenous Infusions
01/2013